2023年
2023年 論文
The rally ‘round the flag effect in third parties: the case of the Russian invasion of Ukraine.
Kentaro Fukumoto, Takahiro Tabuchi.
Journal of Elections, Public Opinion and Parties.(2023)
Efficient selection of knocked-in pluripotent stem cells using a dual cassette cellular elimination system.
Koji Nakade, Satomi Tsukamoto, Kenichi Nakashima, Yuri An, Iori Sato, Jingyue Li, Yuzuno Shimoda, Yasuko Hemmi, Yoshihiro Miwa, Yohei Hayashi.
Cell Rep Methods.(2023)
TAS0313 Plus Pembrolizumab for Post-Chemotherapy Immune Checkpoint Inhibitor-Naïve Locally Advanced or Metastatic Urothelial Carcinoma.
Nishiyama H, Yonese J, Kawahara T, Matsumoto R, Miyake H, Matsubara N, Uemura H, Eto M, Azuma H, Obara W, Terai A, Fukasawa S, Suekane S.
Mol Cancer Ther.(2023)
Multi-omics clustering based on interpretable and discriminative features for cancer subtyping.
Tianyi Shi, Xiucai Ye, Tetsuya Sakurai.
Proceeding of IEEE International Conference on Bioinformatics and Biomedicine (BIBM).(2023)
Collaborative causal inference on distributed data.
Yuji Kawamata, Ryoki Motai, Yukihiko Okada, Akira Imakura, Tetsuya Sakurai.
Expert Systems with Applications.(2023)
Prenatal Exposure to Heavy Metals and Adverse Birth Outcomes: Evidence From an E‐Waste Area in China.
Chen Chen, Chaochen Ma, Qiyao Li, Jin Guo Hang, Jiantong Shen, Shoji F. Nakayama, Teruhiko Kido, Yibin Lin, Hao Feng, Chau‐Ren Jung, Xian liang Sun, Juanlin Lou.
GeoHealth.(2023)
Evaluation of Cognitive and Physical Function Among Older Adults by Their Physical Activity: A Cross-Sectional Kasama Study, Japan.
Jieun Yoon, Kazunori Sasaki, Korin Tateoka, Tetsuaki Arai, Hiroko Isoda, Tomohiro Okura.
Journal of Alzheimer’s Disease.(2023)
Erdafitinib or Chemotherapy in Advanced or Metastatic Urothelial Carcinoma.
Loriot Y, Matsubara N, Park SH, Huddart RA, Burgess EF, Houede N, Banek S, Guadalupi V, Ku JH, Valderrama BP, Tran B, Triantos S, Kean Y, Akapame S, Deprince K, Mukhopadhyay S, Stone NL, Siefker-Radtke AO, THOR Cohort 1 Investigators (Nishiyama H).
N Engl J Med.(2023)
Usefulness of New Criteria for Metabolic Syndrome Optimized for Prediction of Cardiovascular Diseases in Japanese.
Yamazaki Y, Fujihara K, Sato T, Harada Yamada M, Yaguchi Y, Matsubayashi Y, Yamada T, Kodama S, Kato K, Shimano H, Sone H.
J Atheroscler Thromb.(2023)
Rhomboid protease RHBDL4/RHBDD1 cleaves SREBP-1c at endoplasmic reticulum monitoring and regulating fatty acids.
Han SI, Nakakuki M, Nakagawa Y, Wang Y, Araki M, Yamamoto Y, Tokiwa H, Takeda H, Mizunoe Y, Motomura K, Ohno H, Kainoh K, Murayama Y, Aita Y, Takeuchi Y, Osaki Y, Miyamoto T, Sekiya M, Matsuzaka T, Yahagi N, Sone H, Daitoku H, Sato R, Kawano H, Shimano H.
PNAS Nexus.(2023)
Efficacy and safety of axitinib for metastatic renal cell carcinoma: Real-world data on patients with renal impairment.
Minami K, Osawa T, Kojima T, Hara T, Eto M, Takeuchi A, Nakai Y, Ueda K, Ozawa M, Uemura M, Ohba K, Tamura K, Shindo T, Nakagomi H, Takahashi A, Anai S, Yokomizo A, Morizane S, Kimura T, Shimazui T, Miyauchi Y, Mitsuzuka K, Hara H, Yoshimura K, Shiina H, Ito YM, Murai S, Nishiyama H, Shinohara N, Kitamura H.
Urologic Oncology.(2023)
Collaborative analysis for drug discovery by federated learning on non-IID data.
Dong Huang, Xiucai Ye, Ying Zhang, Tetsuya Sakurai.
Methods.(2023)
Microarray Meta-analysis Reveals Comprehensive Effects of 3,4,5-Tricaffeolyquinic Acid in Cell Differentiation and Signaling.
Yu Jia Chen, Farhana Ferdousi, Meriem Bejaoui, Kazunori Sasaki, Hiroko Isoda.
European Journal of Pharmacology.(2023)
Adaptive learning embedding features to improve the predictive performance of SARS-CoV-2 phosphorylation sites.
Shihu Jiao, Xiucai Ye, Chunyan Ao, Tetsuya Sakurai, Quan Zou, Lei Xu.
Bioinformatics.(2023)
C-Terminal Binding Protein 2 Emerges as a Critical Player Linking Metabolic Imbalance to the Pathogenesis of Obesity.
Sekiya M, Kainoh K, Saito K, Yamazaki D, Tsuyuzaki T, Chen W, Kobari Y, Nakata A, Babe H, Shimano H.
J Atheroscler Thromb.(2023)
Tumor immune microenvironment and clinical outcomes in stage IV urothelial cancer: YODO study.
Nishiyama H, Tsuzuki T, Ohyama C, Matsuyama H, Shinozaki K, Hayashi Y, Hayashi N, Koto R, Shin E, Ogawa O.
International Journal of Clinical Oncology.(2023)
Chapter 3: Management of kidney injury caused by cancer drug therapy, from clinical practice guidelines for the management of kidney injury during anticancer drug therapy 2022.
Ando Y, Nishiyama H, Shimodaira H, Takano N, Sakaida E, Matsumoto K, Nakanishi K, Sakai H, Tsukamoto S, Komine K, Yasuda Y, Kato T, Fujiwara Y, Koyama T, Kitamura H, Kuwabara T, Yonezawa A, Okumura Y, Yakushijin K, Nozawa K, Goto H, Matsubara T, Hoshino J, Yanagita M.
International Journal of Clinical Oncology.(2023)
Chapter 2:indications and dosing of anticancer drug therapy in patients with impaired kidney function, from clinical practice guidelines for the management of kidney injury during anticancer drug therapy.
Nishiyama H, Inoue T, Koizumi Y, Kobayashi Y, Kitamura H, Yamamoto K, Takeda T, Yamamoto T, Yamamoto R, Matsubara T, Hoshino J, Yanagita M.
International Journal of Clinical Oncology.(2023)
Hematinic potential of olive leaf extract: Evidence from an in vivo study in mice and a pilot study in healthy human volunteers
Shinji Kondo, Farhana Ferdousi, Jinchang Zhao, Sofya Suidasari, Miki Yokozawa, Ken Yamauchi, Ken-ichi Tominaga, Hiroko Isoda
Nutrients.15(19):4095.(2023)
Transcriptomics and Biochemical Evidence of Trigonelline Ameliorating Learning and Memory Decline in the Senescence-Accelerated Mouse Prone 8 (SAMP8) Model by Suppressing Proinflammatory Cytokines and Elevating Neurotransmitter Release
Sharmin Aktar, Farhana Ferdousi, Shinji Kondo, Tamami Kagawa, Hiroko Isoda
GeroScience:023-00919.(2023)
GR-KLF15 pathway controls hepatic lipogenesis during fasting
Takeuchi Y, Murayama Y, Aita Y, Mehrazad Saber Z, Karkoutly S, Tao D, Katabami K, Ye C, Shikama A, Masuda Y, Izumida Y, Miyamoto T, Matsuzaka T, Kawakami Y, Shimano H, Yahagi N.
FEBS J:16957.(2023)
Investigation into Molecular Brain Aging in Senescence-Accelerated Mouse (SAM) Model Employing Whole Transcriptomic Analysis in Search of Potential Molecular Targets for Therapeutic Interventions
Michitaka Fujiwara, Farhana Ferdousi, and Hiroko Isoda
Int. J. Mol. Sci.24(18):13867.(2023)
Multi-omics clustering for cancer subtyping based on latent subspace learning
Xiucai Ye, Yifan Shang, Tianyi Shi, Weihang Zhang, Tetsuya Sakurai
Computers in Biology and Medicine.164:107223.(2023)
Self-stabilizing performance of γ-oryzanol in oil-in-water emulsions and solid dispersions.
Noamane Taarji, Meryem Bouhoute, Lorena de Oliveira Felipe, Mansour Sobeh, Isao Kobayashi, Marcos A. Neves, Kenichi Tominaga, Hiroko Isoda, Mitsutoshi Nakajima
Heliyon.9(9): e19677.(2023)
An inhaled ACE2 decoy confers protection against SARS-CoV-2 infection in preclinical models.
Urano E, Itoh Y, Suzuki T, Sasaki T, Kishikawa JI, Akamatsu K, Higuchi Y, Sakai Y, Okamura T, Mitoma S, Sugihara F, Takada A, Kimura M, Nakao S, Hirose M, Sasaki T, Koketsu R, Tsuji S, Yanagida S, Shioda T, Hara E, Matoba S, Matsuura Y, Kanda Y, Arase H, Okada M, Takagi J, Kato T, Hoshino A, Yasutomi Y, Saito A, Okamoto T.
Science Translational Medicine.(2023)
Post-COVID health-related quality of life and somatic symptoms: A national survey in Japan.
Kazuhiro Kamata, Hitoshi Honda, Yasuharu Tokuda, Akane Takamatsu, Kiyosu Taniguchi, Kenji Shibuya, Takahiro Tabuchi.
The American Journal of the Medical Sciences.(2023)
Exploring Large MAF Transcription Factors: Functions, Pathology, and Mouse Models with Point Mutations.
Fujino M, Ojima M, Takahashi S.
Genes (Basel).(2023)
A universal method for generating knockout mice in multiple genetic backgrounds using zygote electroporation.
Tomohiro Tamari, Yoshihisa Ikeda, Kento Morimoto, Keiko Kobayashi, Saori Mizuno-Iijima, Shinya Ayabe, Akihiro Kuno, Seiya Mizuno, Atsushi Yoshiki.
Biology Open.(2023)
Intramolecular interaction of NEP regulated by CRM1 ensures the unidirectional transport of M1 for the nuclear. export of influenza viral ribonucleoprotein.
Frontiers in Virology.(2023)
Variant allele frequency changes in TP53 predict pembrolizumab response in patients with metastatic urothelial carcinoma.
Hamada K, Nagumo Y, Kandori S, Tanuma K, Shiga M, Hoshi A, Negoro H, Kojima T, Mathis BJ, Nishiyama H.
Oncology Letters.(2023)
Enhanced early skin treatment for atopic dermatitis in infants reduces food allergy.
Kiwako Yamamoto-Hanada, Tohru Kobayashi, Masashi Mikami, Hywel C. Williams, Hirohisa Saito, Mayako Saito-Abe, Miori Sato, Makoto Irahara, Yumiko Miyaji, Fumi Ishikawa, Kunihiko Tsuchiya, Risa Tamagawa-Mineoka, Yuri Takaoka, Yutaka Takemura, Sakura Sato, Hiroyuki Wakiguchi, Miyuki Hoshi, Osamu Natsume, Fumiya Yamaide, Miwako Seike, Yukihiro Ohya, Kumiko Morita, Eisuke Inoue, Tatsuki Fukuie, Shigenori Kabashima, Yusuke Inuzuka, Koji Nishimura, Kenji Toyokuni, Hiroya Ogita, Tomoyuki Kiguchi, Kazue Yoshida, Jumpei Saito, Hajime Hosoi, Norito Katoh, Mariko Morimoto, Koji Masuda, Makoto Kameda, Amane Shigekawa, Koji Yamasaki, Megumi Nagai, Motohiro Ebisawa, Tomoyuki Asaumi, Takaaki Itonaga, Shunji Hasegawa, Hiroki Yasudo, Mizuho Nagao, Takao Fujisawa, Ryuhei Yasuoka, Toshiharu Fujiyama, Naoki Shimojo, Taiji Nakano, Yasuto Kondo, Yuji Mori, Takahiro Kawaguchi, Masaki Futamura, Kazumitsu Sugiura, Akiyo Nagai, Sachiko Kaburagi, Hiroshi Kitazawa, Hiroshi Kido, Shoji F. Nakayama.
Journal of Allergy and Clinical Immunology.(2023)
DC-SHAP Method for Consistent Explainability in Privacy-Preserving Distributed Machine Learning.
Anna Bogdanova, Akira Imakura, Tetsuya Sakurai.
Human-Centric Intelligent Systems.(2023)
Sexual orientation was associated with intention to be vaccinated with a smallpox vaccine against mpox: A cross-sectional preliminary survey in Japan.
Daisuke Hori, Yudai Kaneda, Akihiko Ozaki, Takahiro Tabuchi.
Vaccine.(2023)
Plasma circulating tumor DNA profiling in patients with chemo-refractory germ cell tumors.
Sakka S, Kandori S, Kawai K, Kojima T, Nitta S, Chihara I, Nagumo Y, Kawahara T, Mathis BJ, Ishihara M, Shinohara N, Kishida T, Ukimura O, Nishimura K, Kobayashi Y, Nishiyama H.
International Journal of Urology.(2023)
Short-term association of air pollution with lung cancer mortality in Osaka, Japan.
Chaochen Ma, Chau-Ren Jung, Shoji F. Nakayama, Takahiro Tabuchi, Yukiko Nishihama, Haruka Kudo, Toshitaka Morishima, Yuko Ohno, Tomotaka Sobue, Isao Miyashiro
Environmental Research.(2023)
Systemic surveillance of an emerging picornavirus among cattle and sheep in China.
Ji C, Zhang Y, Feng Y, Zhang X, Ma J, Pan Z, Kawaguchi A, Yao H.
Microbiology Spectrum.(2023)
Generation and mutational analysis of a transgenic murine model of the human MAF mutation.
Fujino M, Ojima M, Ishibashi S, Mizuno S, Takahashi S.
American Journal of Medical Genetics Part A.(2023)
Loss of CtBP2 may be a mechanistic link between metabolic derangements and progressive impairment of pancreatic β cell function
Sekiya M, Ma Y, Kainoh K, Saito K, Yamazaki D, Tsuyuzaki T, Chen W, Adi Putri PIP, Ohno H Miyamoto T, Takeuchi Y, Murayama Y, Sugano Y, Osaki Y, Iwasaki H, Yahagi N, Suzuki H, Motomura K, Matsuzaka T, Murata K, Mizuno S, Takahashi S, Shimano H.
Cell Rep.42(8):112914.(2023)
Multi-view Network Embedding with Structure and Semantic Contrastive Learning
Yifan Shang, Xiucai Ye, Tetsuya Sakurai
Proceedings of the IEEE International Conference on Multimedia and Expo (ICME):870-875.(2023)
Effects of Desert Olive Tree Pearls Containing High Hydroxytyrosol Concentrations on the Cognitive Functions of Middle-Aged and Older Adults
Jieun Yoon, Kazunori Sasaki, Iku Nishimura, Haruna Hashimoto, Tomohiro Okura, Hiroko Isoda
Nutrients.15(14):3234.(2023)
Data collaboration analysis in predicting diabetes from a small amount of health checkup data
Go Uchitachimoto, Noriyoshi Sukegawa, Masayuki Kojima, Rina Kagawa, Takashi Oyama, Yukihiko Okada, Akira Imakura, Tetsuya Sakurai
Scientific Reports.13(1):11820.(2023)
A Rare Olive Compound Oleacein Improves Lipid and Glucose Metabolism, and Inflammatory Functions: A Comprehensive Whole-Genome Transcriptomics Analysis in Adipocytes Differentiated from Healthy and Diabetic Adipose Stem Cells
Rui Wang, Munkhzul Ganbold, Farhana Ferdousi, Kenichi Tominaga, Hiroko Isoda
Int. J. Mol. Sci.24(13):10419.(2023)
Common and Unique Features Learning in Multi-view Network Embedding
Yifan Shang, Xiucai Ye, Tetsuya Sakurai
Proceeding of International Joint Conference on Neural Networks (IJCNN):1-8.(2023)
Obesity-induced metabolic imbalance allosterically modulates CtBP2 to inhibit PPAR-alpha transcriptional activity
Saito K, Sekiya M, Kainoh K, Yoshino R, Hayashi A, Han SI, Araki M, Ohno H, Takeuchi Y, Tsuyuzaki T, Yamazaki D, Wanpei C, Hada L, Watanabe S, Paramita Adi Putri PI, Murayama Y, Sugano Y, Osaki Y, Iwasaki H, Yahagi N, Suzuki H, Miyamoto T, Matsuzaka T, Shimano H.
J Biol Chem.299(7):104890.(2023)
Molecular language models: RNNs or transformer?
Yangyang Chen, Zixu Wang, Xiangxiang Zeng, Yayang Li, Pengyong Li, Xiucai Ye, Tetsuya Sakurai.
Briefings in Functional Genomics.22(4):392-400.(2023)
Non-readily identifiable data collaboration analysis for multiple datasets including personal information
Akira Imakura, Tetsuya Sakurai, Yukihiko Okada, Tomoya Fujii, Teppei Sakamoto, Hiroyuki Abe
Information Fusion.98:101826.(2023)
Efficacy and Safety of Bladder Preservation Therapy in Combination with Atezolizumab and Radiation Therapy (BPT-ART) for Invasive Bladder Cancer: Interim Analysis from a Multicenter, Open-label, Prospective Phase 2 Trial
Kimura T, Ishikawa H, Nagumo Y, Sekino Y, Kageyama Y, Ushijima H, Kawai T, Yamashita H, Azuma H, Nihei K, Takemura M, Hashimoto K, Maruo K, Tsuzuki T, Nishiyama H
Int J Radiat Oncol Biol Phys.117(3):644-651.
Another use of SMOTE for interpretable data collaboration analysis
Akira Imakura, Masateru Kihira, Yukihiko Okada, Tetsuya Sakurai
Expert Systems with Applications.228:120385.(2023)
Solid acid-catalyzed one-step synthesis of oleacein from oleuropein
Yasuhiro Shimamoto, Tadahiro Fujitani, Eriko Uchiage, Hiroko Isoda, Ken-Ichi Tominaga
Scientific Reports.13(1):8275.(2023)
A Descriptive Whole-Genome Transcriptomics Study in a Stem Cell-Based Tool Predicts Multiple Tissue-Specific Beneficial Potential and Molecular Targets of Carnosic Acid
Farhana Ferdousi, Kazunori Sasaki, Satoshi Fukumitsu, Hidetoshi Kuwata, Mitsutoshi Nakajima, Hiroko Isoda
Int. J. Mol. Sci.24(9):8077.(2023)
Effects of home-based manual dexterity training on cognitive function among older adults: a randomized controlled trial
Jaehoon Seol, Namhoon Lim, Koki Nagata, Tomohiro Okura
European Review of Aging and Physical Activity.20(1):9.(2023)
Botryococcus terribilis Ethanol Extract Exerts Anti-inflammatory Effects on Murine RAW264 Cells
S Takahashi, F Ferdousi, S Yamamoto, A Hirano, S Nukaga, H Nozaki, H Isoda
Int. J. Mol. Sci.24(7):6666.(2023)
Network meta-analysis of glucose-lowering drug treatment regimens with the potential risk of hypoglycemia in patients with type 2 diabetes mellitus in terms of glycemic control and severe hypoglycemia
Kodama S, Fujihara K, Ishiguro H, Matsubayashi Y, Kitazawa M, Iwanaga M, Yamada T, Kato K Nakagawa Y, Tanaka S, Shimano H, Sone H.
J Investig Med.71(4):400-410.(2023)
Large Maf transcription factor family is a major regulator of fast type IIb myofiber determination
Sadaki S, Fujita R, Hayashi T, Nakamura A, Okamura Y, Fuseya S, Hamada M, Warabi E, Kuno A, Ishii A, Muratani M, Okada R, Shiba D, Kudo T, Takeda S, Takahashi S.
Cell Rep.42(4):112289.(2023)
Transcription factor c-Maf deletion improves streptozotocin-induced diabetic nephropathy by directly regulating Sglt2 and Glut2
Fujino M, Morito N, Hayashi T, Ojima M, Ishibashi S, Kuno A, Koshiba S, Yamagata K, Takahashi S.
JCI Insight.8(6):e163306.(2023)
Effect of Alkali Metal Cations on the Unilamellar Vesicle of a Squalene Bearing 18-Crown-6
Tran Ngoc Linh, Takashi Arimura, Ken-Ichi Tominaga, Hiroko Isoda, Masato Kawasaki, Naruhiko Adachi
ACS Omega.8(12):11583-11587.(2023)
Takotsubo cardiomyopathy with left ventricle thrombus caused by subacute thyroiditis
Yamazaki D, Osaki Y, Suzuki H, Shimano H.
BMJ Case Rep.16(3):e250540.(2023)
The fatty acid elongase Elovl6is crucial for hematopoietic stem cell engraftment and leukemia propagation
Kiyoki Y, Kato T, Kito S, Matsuzaka T, Morioka S, Sasaki J, Makishima K, Sakamoto T, Nishikii H, Obara N, Sakata-Yanagimoto M, Sasaki T, Shimano H, Chiba S.
Leukemia.37(4):910-913.(2023)
Deep generative model for drug design from protein target sequence
Yangyang Chen, Zixu Wang, Lei Wang, Jianmin Wang, Pengyong Li, Dongsheng Cao, Xiangxiang Zeng, Xiucai Ye, Tetsuya Sakurai
Journal of Cheminformatics.15(1):38.(2023)
Interactive gene identification for cancer subtyping based on multi-omics clustering
Xiucai Ye, Tianyi Shi, Yaxuan Cui, Tetsuya Sakurai
Methods.211:61-67.(2023)
MafB Maintains β-Cell Identity under MafA-Deficient Conditions
Deng Z, Kuno A, Ojima M, Takahashi S.
Mol Cell Biol.42(8):e0054121.(2022)
New balance capability index as a screening tool for mild cognitive impairment
Suzuki Y, Tsubaki T, Nakaya K, Kondo G, Takeuchi Y, Aita Y, Murayama Y, Shikama A, MasudaY, Suzuki H, Kawakami Y, Shimano H, Arai T, Hada Y, Yahagi N.
BMC Geriatr.23(1):74.(2023)
Distortion-free PCA on sample space for highly variable gene detection from single-cell RNA-seq data
Momo Matsuda, Yasunori Futamura, Xiucai Ye, Tetsuya Sakurai
Frontiers in Computer Science.17(1):171310.(2023)
Identification of key microRNAs regulating ELOVL6 and glioblastoma tumorigenesis
Nurani Istiqamah, Takashi Matsuzaka, Momo Shimizu, Kaori Motomura, Hiroshi Ohno, Shiho Hasebe, Rahul Sharma, Yuka Okajima, Erika Matsuda, Song-Iee Han, Yuhei Mizunoe, Yoshinori Osaki, Yuichi Aita, Hiroaki Suzuki, Hirohito Sone, Yoshinori Takeuchi, Motohiro Sekiya, Naoya Yahagi, Yoshimi Nakagawa, Hitoshi Shimano
BBA Advances.3:100078.(2023)
Glucocorticoids coordinate the bladder peripheral clock and diurnal micturition pattern in mice
Chihara I, Negoro H, Kono J, Nagumo Y, Tsuchiya H, Kojo K, Shiga M, Tanaka K, Kandori S, Mathis BJ, Nishiyama H.
Commun Biol. 6(1):81.(2023)
Empagliflozin in Patients with Chronic Kidney Disease
The EMPA-KIDNEY Collaborative Group; Herrington WG, Staplin N, Wanner C, Green JB, Hauske SJ, Emberson JR, Preiss D, Judge P, Mayne KJ, Ng SYA, Sammons E, Zhu D, Hill M, Stevens W, Wallendszus K, Brenner S, Cheung AK, Liu ZH, Li J, Hooi LS, Liu W, Kadowaki T, Nangaku M, Levin A, Cherney D, Maggioni AP, Pontremoli R, Deo R, Goto S, Rossello X, Tuttle KR, Steubl D, Petrini M, Massey D, Eilbracht J, Brueckmann M, Landray MJ, Baigent C, Haynes R.
N Engl J Med.388(2):117-127.(2023)
Olive Leaves Extract and Oleuropein Improve Insulin Sensitivity in 3T3-L1 Cells and in High-Fat Diet-Treated Rats via PI3K/AkT Signaling Pathway
Fatma Hadrich, Asma Mahmoudi, Mohamed Chamkha, Hiroko Isoda, Sami Sayadi
Oxid Med Cell Longev.2023:6828230.(2023)