2024年

Genetic and Functional Analyses of Patients with Marked Hypo-High-Density Lipoprotein Cholesterolemia.
Furuta Y, Osaki Y, Nakagawa Y, Han SI, Araki M, Shikama A, Ohuchi N, Yamazaki D, Matsuda E, Nohara S, Mizunoe Y, Kainoh K, Suehara Y, Ohno H, Takeuchi Y, Miyamoto T, Murayama Y, Sugano Y, Iwasaki H, Hirano KI, Koseki M, Nakano S, Tokiwa H, Sekiya M, Yahagi N, Matsuzaka T, Nakamagoe K, Tomidokoro Y, Mitsui J, Tsuji S, Suzuki H, Shimano H.
Journal of Atherosclerosis and Thrombosis.(2024)

A Comparative Transcriptomics Analysis Reveals Ethylene Glycol Derivatives of Squalene Ameliorate Excessive Lipogenesis and Inflammatory Response in 3T3-L1 Preadipocytes.
Yu Cheng, Farhana Ferdousi, Bryan Angelo Foronda, Tran Ngoc Linh, Munkhzul Ganbold, Akira Yada, Takashi Arimura, Hiroko Isoda.
Heliyon.(2024)

Zinc binding of a Cys2His2-type zinc finger proteins is enhanced by the interaction with DNA.
Hajdu B, Hunyadi-Gulyas E, Kato K, Kawaguchi A, Nagata K, Gyurcsik B.
JBIC Journal of Biological Inorganic Chemistry.(2024)

Multi-party collaborative drug discovery via federated learning.
Dong Huang, Xiucai Ye, Tetsuya Sakurai.
Computers in Biology and Medicine.(2024)

Adult genitourinary sarcoma: analysis using hospital-based cancer registry data in Japan.
Nitta S, Kandori S, Kojo K, Suzuki S, Hamada K, Chihara I, Shiga M, Sakka S, Nagumo Y, Kimura T, Mathis BJ, Negoro H, Okuyama A, Higashi T, Nishiyama H.
BMC Cancer.(2024)

Comprehensive transcriptome profiling of antioxidant activities by glutathione in human HepG2 cells.
Yoshiaki Uchida, Farhana Ferdousi, Shinya Takahashi, Hiroko Isoda.
molecules.(2024)

Keratin Microspheres as Promising Tool for Targeting Follicular Growth.
Meriem Bejaoui, Wey Yih Heah, Aprill Kee Oliva Mizushima, Mitsutoshi Nakajima, Hiroshi Yamagishi, Yohei Yamamoto, Hiroko Isoda.
ACS Applied Bio Materials.(2024)

Prognostic impact of histological discordance between transurethral resection and radical cystectomy.
Matsuda A, Taoka R, Miki J, Saito R, Fukuokaya W, Hatakeyama S, Kawahara T, Fujii Y, Kato M, Sazuka T, Sano T, Urabe F, Kashima S, Naito H, Murakami Y, Miyake M, Daizumoto K, Matsushita Y, Hayashi T, Inokuchi J, Sugino Y, Shiga K, Yamaguchi N, Iio H, Yasue K, Abe T, Nakanishi S, Matsumura M, Fujii M, Nishihara K, Matsumoto H, Tatarano S, Wada K, Sekito S, Maruyama R, Nishiyama N, Nishiyama H, Kitamura H, Matsui Y; Japanese Urological Oncology Group.
BJU Int.(2024)

Cross-Sectional and Longitudinal Associations between Forearm Bone Mineral Density and Anthropometry in Adult Japanese Men and Women.
Ishizawa M, Fujihara K, Yachida J, Ikeda I, Sato T, Yamada T, Kobayashi A, Tanaka S, Nakagawa Y, Matsuzaka T, Shimano H, Tashiro M, Kodama S, Kato K, Sone H.
Journal of Bone Metabolism.(2024)

Bioactive TNIIIA2 Sequence in Tenascin-C Is Responsible for Macrophage Foam Cell Transformation; Potential of FNIII14 Peptide Derived from Fibronectin in Suppression of Atherosclerotic Plaque Formation.
Iyoda T, Ohishi A, Wang Y, Yokoyama MS, Kazama M, Okita N, Inouye S, Nakagawa Y, Shimano H, Fukai F.
Int J Mol Sci.(2024)

Correction to: Clinical questions and good practice statements of clinical practice guidelines for management of kidney injury during anticancer drug therapy 2022.
Yanagita M, Muto S, Nishiyama H, Ando Y, Hirata S, Doi K, Fujiwara Y, Hanafusa N, Hatta T, Hoshino J, Ichioka S, Inoue T, Ishikura K, Kato T, Kitamura H, Kobayashi Y, Koizumi Y, Kondoh C, Matsubara T, Matsubara K, Matsumoto K, Okuda Y, Okumura Y, Sakaida E, Shibagaki Y, Shimodaira H, Takano N, Uchida A, Yakushijin K, Yamamoto T, Yamamoto K, Yasuda Y, Oya M, Okada H, Nangaku M, Kashihara N.
Clinical and Experimental Nephrology.(2024)

Clinical questions and good practice statements of clinical practice guidelines for management of kidney injury during anticancer drug therapy 2022.
Yanagita M, Muto S, Nishiyama H, Ando Y, Hirata S, Doi K, Fujiwara Y, Hanafusa N, Hatta T, Hoshino J, Ichioka S, Inoue T, Ishikura K, Kato T, Kitamura H, Kobayashi Y, Koizumi Y, Kondoh C, Matsubara T, Matsubara K, Matsumoto K, Okuda Y, Okumura Y, Sakaida E, Shibagaki Y, Shimodaira H, Takano N, Uchida A, Yakushijin K, Yamamoto T, Yamamoto K, Yasuda Y, Oya M, Okada H, Nangaku M, Kashihara N.
Clin Exp Nephrol.(2024)

Updated Overall Survival by Circulating Tumor DNA Status from the Phase 3 IMvigor010 Trial: Adjuvant Atezolizumab Versus Observation in Muscle-invasive Urothelial Carcinoma.
Powles T, Assaf ZJ, Degaonkar V, Grivas P, Hussain M, Oudard S, Gschwend JE, Albers P, Castellano D, Nishiyama H, Daneshmand S, Sharma S, Sethi H, Aleshin A, Shi Y, Davarpanah N, Carter C, Bellmunt J, Mariathasan S.
European Urology.(2024)

Anti-obesity and Hypolipidemic Potential of Nitraria retusa Extract in overweight/obese Women: A Randomized, Double-Blind, Placebo- Controlled Pilot Study.
Aicha Laouani, Hana Nasrallah, Awatef Sassi, Farhana Ferdousi, Feten Zar Kalai, Yosra Hasni, Hiroko Isoda, Saad Saguem.
Nutrients.(2024)

Macrophage SREBP1 regulates skeletal muscle regeneration.
Oishi Y, Koike H, Kumagami N, Nakagawa Y, Araki M, Taketomi Y, Miki Y, Matsuda S, Matsuzaka T, Ozawa H, Shimano H, Murakami M, Manabe I.
Front Immunol.(2024)

Modulation of mitochondrial activity by sugarcane (Saccharum officinarum L.) top extract and its bioactive polyphenols: a comprehensive transcriptomics analysis in C2C12 myotubes and HepG2 hepatocytes.
Kengo Iwata, Farhana Ferdousi, Yoshinobu Arai, Hiroko Isoda.
Natural Products and Bioprospecting.(2024)

Novel Soybean Variety Lacking Raffinose Synthase 2 Activity.
Miki Maeda, Kyoko Toda, Akito Kaga.
ACS Omega.(2024)

The association of positive emotions with absenteeism and presenteeism in Japanese workers.
Chong Chen, Ryo Okubo, Kosuke Hagiwara, Tomohiro Mizumoto, Shin Nakagawa, Takahiro Tabuchi.
Journal of Affective Disorders.(2024)

Single-Cell Transcriptome Profiling of Pancreatic Islets From Early Diabetic Mice Identifies Anxa10 for Ca2+ Allostasis Toward β-Cell Failure.
Motomura K, Matsuzaka T, Shichino S, Ogawa T, Pan H, Nakajima T, Asano Y, Okayama T, Takeuchi T, Ohno H, Han SI, Miyamoto T, Takeuchi Y, Sekiya M, Sone H, Yahagi N, Nakagawa Y, Oda T, Ueha S, Ikeo K, Ogura A, Matsushima K, Shimano H.
Diabetes.(2024)

Concentrations of neonicotinoid insecticides and their metabolites in multiple urine samples collected from pregnant women in Japan.
Neeranuch Suwannarin, Tomohiko Isobe, Yukiko Nishihama, Yuki Ito, Michihiro Kamijima, Takeshi Ebara, Mayumi Sugiura-Ogasawara, Naomi Nishikawa, Kunihiko Nakai, Yumina Minamikawa, Shoji F. Nakayama.
Environmental Research.(2024)

Erdafitinib in BCG-treated high-risk non-muscle-invasive bladder cancer.
Catto JWF, Tran B, Rouprêt M, Gschwend JE, Loriot Y, Nishiyama H, Redorta JP, Daneshmand S, Hussain SA, Cutuli HJ, Procopio G, Guadalupi V, Vasdev N, Naini V, Crow L, Triantos S, Baig M, Steinberg G.
Ann Oncol.(2024)

Urological Cancer Current Status and Challenges of Liquid Biopsy in Urologic Tumors.
Nishiyama H.
癌と化学療法.(2024)

Impact of primary kidney disease on the effects of empagliflozin in patients with chronic kidney disease: secondary analyses of the EMPA-KIDNEY trial.
EMPA-KIDNEY Collaborative Group (Shimano H, 他）.
The Lancet Diabetes & Endocrinology.(2024)

Effects of empagliflozin on progression of chronic kidney disease: a prespecified secondary analysis from the empa-kidney trial.
EMPA-KIDNEY Collaborative Group (Shimano H, 他）.
The Lancet Diabetes & Endocrinology.(2024)

Label-free imaging of intracellular structures in living mammalian cells via external apodization phase-contrast microscopy.
Ohno H, Nishimura T, Kainoh K, Ohash Yi, Onodera N, Kano M, Sari LN, Masuda M, Tamura Y, Hayashi Y, Yamamoto Y, Takahashi S, Mishima Y, Yoneyama Y, Takeuchi Y, Sekiya M, Matsuzaka T, Miyamoto T, Shimano H.
bioRxiv.(2024)

Inductively Coupled Plasma Mass Spectrometry Performance for the Measurement of Key Serum Minerals: A Comparative Study With Standard Quantification Methods.
Kojo K, Oguri T, Tanaka T, Ikeda A, Shimizu T, Fujimoto S, Nakazono A, Nagumo Y, Kandori S, Negoro H, Nishiyama H.
Journal of Clinical Laboratory Analysis.(2024)

Developing a battery of physical performance tests to predict functional disability in Japanese older adults: A longitudinal study from the Kasama study.
Lim N, Tsunoda K, Nagata K, Asano Y, Seol J, Jindo T, Tsuji T, Okura T.
Geriatrics Gerontology International.(2024)

Impact of microgravity and lunar gravity on murine skeletal and immune systems during space travel.
Okamura Y, Gochi K, Ishikawa T, Hayashi T, Fuseya S, Suzuki R, Kanai M, Inoue Y, Murakami Y, Sadaki S, Jeon H, Hayama M, Ishii H, Tsunakawa Y, Ochi H, Sato S, Hamada M, Abe C, Morita H, Okada R, Shiba D, Muratani M, Shinohara M, Akiyama T, Kudo T, Takahashi S.
Scientific Reports.(2024)

移植医療を革新する：自己組織化抗酸化ナノ粒子（RNP）の可能性
高橋 一広; 長崎幸夫; 杉朋幸; 小田竜也
Precision medicine.(2024)

Phospholipase D2 downregulates interleukin-1β secretion from tumor-associated macrophages to suppress bladder cancer progression.
Hamada K, Nagumo Y, Kandori S, Isoda B, Suzuki S, Sano K, Sakka S, Tanuma K, Nitta S, Shiga M, Negoro H, Mathis BJ, Funakoshi Y, Nishiyama H.
Cancer Science.(2024)

Cancer subtype identification by multi-omics clustering based on interpretable feature and latent subspace learning.
Shi T,i Ye X, Huang D, Sakurai T.
Methods.(2024)

Cross-sectional study of the optimal types of physical exercise for cognitive function in older Japanese adults.
Nagata K, Shibuya K, Fujii Y, Seol J, Jindo T, Okura T.
Geriatrics Gerontology International.(2024)

Transcriptomic evidence of black soybean ethanolic extract and 2-aminobutyric acid in suppressing neuroinflammation and enhancing synaptic transmission.
Aktar S, Kato A, Toda K, Takahashi S, Maeda-Yamamoto M, Ferdousi F, Isoda H.
Biomedicine & Pharmacotherapy.(2024)

MAFB in Macrophages Regulates Prostaglandin E2–Mediated Lipid Mediator Class Switch through ALOX15 in Ischemic Acute Kidney Injury.
Kanai M, Nishino T, Daassi D, Kimura A, Liao CW, Shahri ZJ, Wakimoto A, Gogoleva N, Usui T, Morito N, Arita M, Takahashi S, Hamada M
The Journal of Immunology.(2024)

Nuclear reorganization by NPM1-mediated phase separation triggered by adenovirus core protein VII.
Genoveso MJ, Okuwaki M, Kato K, Nagata K, Kawaguchi A.
Microbiology Spectrum.(2024)

An interpretable deep learning model predicts RNA–small molecule binding sites.
Xi W, Wang R, Wang L, Ye X,Liu M, Sakurai T.
Future Generation Computer Systems.(2024)

Comparison of Neurogenesis Promotion Effects between Cinnamoylquinic Acids in Neural Stem Cells from Adult Mice Brains.
Lin H, Sasaki K, Ferdousi F, Isoda H.
ACS Chemical Neuroscience.(2024)

A Novel Amphiphilic Squalene-based Compound with Open-chain Polyethers Reduces Malignant Melanoma Metastasis In-vitro and In-vivo.
Zhang Y, Bejaoui M, Linh TN, Arimura T, Isoda H.
Cell Communication and Signaling.(2024)

Deciphering the Complex Characterization of Coding LncRNA.
Tianyuan Liu T, Ye X, Sakurai T.
International Joint Conference on Neural Networks (IJCNN).(2024)

CyclePermea: Membrane Permeability Prediction of Cyclic Peptides with a Multi-Loss Fusion Network.
Zixu Wang; Yangyang Chen; Xiucai Ye; Tetsuya Sakurai.
International Joint Conference on Neural Networks (IJCNN).(2024)

Maediastinal germ cell tumors: analysis using hospital-based cancer registry data in Japan.
Takahashi R, Nitta S, Kandori S, Suzuki S, Hamada K, Tanuma K, Kojo K, Shiga M, Sakka S, Nagumo Y, Mathis BJ, Hoshi A, Negoro H, Okuyama A, Higashi T, Nishiyama H.
International Journal of Clinical Oncology.(2024)

Dietary medium-chain fatty acids reduce hepatic fat accumulation via activation of a CREBH-FGF21 axis.
Cao Y, Araki M, Nakagawa Y, Deisen L, Lundsgaard A, Kanta JM, Holm S, Johann K, Brings Jacobsen JC, Jähnert M, Schürmann A, Kiens B, Clemmensen C, Shimano H, Fritzen AM, Kleinert M.
Mol Metab.(2024)

Variability of urinary albumin to creatinine ratio and eGFR are independently associated with eGFR slope in Japanese with type 2 diabetes: a three-year, single-center, retrospective cohort study.
Matsuda T, Osaki Y, Maruo K, Matsuda E, Suzuki Y, Suzuki H, Mathis BJ, Shimano H, Mizutani M.
BMC Nephrology.(2024)

Objective Evaluation of Gaze Location Patterns Using Eye Tracking During Cystoscopy and Artificial Intelligence-Assisted Lesion Detection.
Ikeda A, Izumi K, Katori K, Nosato H, Kobayashi K, Suzuki S, Kandori S, Sanuki M, Ochiai Y, Nishiyama H.
Journal of Endourology.(2024)

TNFSF9 Is Associated with Favorable Tumor Immune Microenvironment in Patients with Renal Cell Carcinoma Who Are Treated with the Combination Therapy of Nivolumab and Ipilimumab.
Isoda B, Kandori S, Sazuka T, Kojima T, Nitta S, Shiga M, Nagumo Y, Fujimoto A, Arai T, Sato H, Mathis BJ, Wu CL, Jan YH, Ichikawa T, Nishiyama H.
International Journal of  Molecular Sciences. (2024)

Abnormal saturated fatty acids and sphingolipids metabolism in asthma.
Yoshida K, Morishima Y, Ishii Y, Mastuzaka T, Shimano H, Hizawa N.
Respiratory Investigation.(2024)

Macrocyclic Azapeptide Nitriles: Structure-Based Discovery of Potent SARS-CoV-2 Main Protease Inhibitors as Antiviral Drugs.
Breidenbach J, Voget R, Si Y, Hingst A, Claff T, Sylvester K, Wolf V, Krasniqi V, Useini A, Sträter N, Ogura Y, Kawaguchi A, Müller CE, Gütschow M.
Journal of Medicinal Chemistry.(2024)

Triethylene Glycol Squalene Improves Hair Regeneration by Maintaining the Inductive Capacity of Human Dermal Papilla Cells and Preventing Premature Aging.
Bejaoui M, Mizushima AKO, Linh TN, Arimura T, Tominaga K, Isoda H.
ACS Pharmacol. Transl. Sci.(2024)

A rare olive compound oleacein functions as a TrkB agonist and mitigates neuroinflammation both in vitro and in vivo.
Wakasugi D, Kondo S, Ferdousi F, Mizuno S, Yada A, Tominaga K, Takahashi S, Isoda H.
Cell Communication and Signaling.(2024)

A new clustering model based on the seminal plasma/serum ratios of multiple trace element concentrations in male patients with subfertility.
Tanaka T, Kojo K, Nagumo Y, Ikeda A, Shimizu T, Fujimoto S, Kakinuma T, Uchida M, Kimura T, Kandori S, Negoro H, Nishiyama H.
Reproductive Medicine and Biology.(2024)

Detection of Active SARS-CoV-2 3CL Protease in Infected Cells Using Activity-Based Probes with a 2,6-Dichlorobenzoyloxymethyl Ketone Reactive Warhead.
Yamauchi Y, Konno, S, Omura N, Yoshioka N, Hingst A, Gütschow M, Müller CE, Taguchi A, Taniguchi A, Kawaguchi A, Hayashi Y.
ACS Chemical Biology.(2024)

Toward the Application of Differential Privacy to Data Collaboration.
Yamashiro H, Omote K, Imakura A, Sakurai T.
IEEE Access. (2024)

A Machine Learning Model to Predict the Histology of Retroperitoneal Lymph Node Dissection Specimens.
Nitta S, Kojima T, Gido M, Nakagawa S, Kakeya H, Kandori S, Kawahara T, Mathis BJ, Kawai K, Negoro H, Nishiyama H.
Anticancer Research.(2024)

Renal Hemodynamic and Functional Changes in Patients with ADPKD.
Ishii R, Kai H, Nakajima K, Harada T, Akiyama T, Okada E, Tsunoda R, Usui T, Mase K, Morito N, Saito C, Usui J, Yamagata K.
Kidney360.(2024)

地域在住高齢者における身体活動とアパシーとの関連に関する縦断的検討
徳永智史，辻大士，藤井啓介，井上大樹，寺岡かおり，立岡光臨，庄子拓良，大藏倫博.
日本老年医学会雑誌.(2024)

Comparative Analysis of Olive-Derived Phenolic Compounds’ Pro-Melanogenesis Effects on B16F10 Cells and Epidermal Human Melanocytes.
Cho J, Bejaoui M, Tominaga K, Isoda H.
International Journal of  Molecular Sciences.(2024)

Gut microbiota of one-and-a-half-year-old food-allergic and healthy children.
Hara M, Suzuki H, Hayashi D, Morii W, Nakamura T, Kiyoki K,Hara H, Ishii R, Noguchi E, Takada H.
Allergology International.(2024)

Patient characteristics correlate with diagnostic performance of photodynamic diagnostic assisted transurethral resection of bladder tumors: A retrospective, single-center study.
Suzuki S, Nagumo Y, Ikeda A, Kojo K, Nitta S, Chihara I, Shiga M, Kawahara T, Kandori S, Hoshi A, Negoro H, Mathis BJ, Nishiyama H.
Photodiagnosis and Photodynamic Therapy.(2024)

DiffSeqMol: A non-autoregressive diffusion-based approach for molecular sequence generation and optimization.
Wang Z, Chen Y, Guo X, Li Y, Li P, Li C, Ye X, Sakurai T.
Current Bioinformatics. (2024)